A standardized protocol for managing patients immediately before, during and after colorectal operations not only improved clinical outcomes, but also it significantly reduced overall hospital costs, a new UC-led study shows.
This study, one of the first to investigate hospital costs associated with an enhanced recovery pathway for colorectal patients, was published in advance of print publication in the Journal of the American College of Surgeons.
"The enhanced recovery protocol provides clinical benefit by getting surgical patients to recover quicker, use less narcotic medication, and have a smoother recovery that gets them out of the hospital and hopefully back to work faster. This study shows there is financial benefit from using the standardized pathway as well,” says study author Ian Paquette, MD, an associate professor of surgery at the University of Cincinnati (UC) College of Medicine, a surgeon with UC Health and corresponding author of the study.
Guidelines for standardizing the care of colorectal surgery patients have been established by the American Society of Colon and Rectal Surgeons (ASCRS) and the Society of American Gastrointestinal and Endoscopic Surgeons (SAGES). These guidelines were updated in 2017.
Previous studies have shown that these protocols reduce overall complications and length of stay and improve patient satisfaction. The studies have focused on clinical aspects of care, rather than cost, or they involved estimations of the cost of following a standardized protocol. This is one of the first published studies to detail the effect on cost of implementing a pathway for colorectal surgery patients.
Researchers from this study compared outcomes and costs for two groups of patients: 160 patients who underwent colorectal procedures one year before an enhanced recovery program was instituted in 2016 and 146 patients who had procedures in the year following universal adoption of the program. Patients in the study underwent operations to treat diverticulitis, colon polyp removal, cancer, inflammatory bowel diseaseor prolapse. The enhanced recovery program standardized preoperative bowel preparation, fluid management, pain control, early ambulation and return to a normal diet.
The study found that the hospital length of stay was two days shorter for patients in the enhanced recovery group. Fewer patients in this group had lack of normal bowl function (6 percent vs. 20 percent). These patients were able to discontinue pain medication one day after surgery, compared with three days post-surgery for patients in the other group and reduce narcotic use. Patients in the enhanced recovery program required 212 morphine equivalent units; patients in the other group required 720 morphine equivalent units.
Total direct hospital costs were $1,717 lower per patient in the enhanced recovery group, which translates into an annual savings of more than $250,000. Daily pharmacy costs per patient were higher ($477 vs. $318). However, total pharmacy costs were $325 less in the enhanced recovery group.
Findings also addressed several principal concerns associated with the adoption of enhanced recovery protocols for colorectal surgery patients, one being slow motility, or ileus.
"Surgeons would wait as long as possible to feed patients after colorectal surgery because of the feeling that the intestinal tract was not ready for food yet,” says Paquette. "We’ve seen in the literature that it’s very safe to feed patients immediately after their operations. By restricting fluids, changing the pain management regimen, mobilizing the patient sooner and putting all these steps together as an organized pathway, we’re seeing that the return of normal gastrointestinal function is faster and patients get out of the hospital sooner."
Enhanced recovery pathways have not been widely implemented because of the concern that they involve the use of high-cost pharmaceuticals, he adds.
"Narcotics, which are commonly used in managing pain after surgery, are very inexpensive,” Paquette says. "Medications recommended in enhanced recovery protocols, such as intravenous acetaminophen, ibuprofen and alvimopan, are expensive and increase daily pharmacy costs. Our study showed that the enhanced recovery pathway decreased total pharmacy cost as well as the total cost of hospitalization.
"The evidence is overwhelming that enhanced recovery pathways lead to a better recovery, get patients back to a normal lifestyle in a quicker manner, and minimize the amount of narcotics, which may help with the ongoing opioid epidemic. This study shows they also lower hospital costs.”
Paquette cites no conflict of interest.